Mixtral 8x22B on Mac Studio M5 Ultra 256 GB
140.63B (39B active) on 256 GB at 1,200 GB/s. Hardware details · Model details
Yes. Mixtral 8x22B fits on Mac Studio M5 Ultra 256 GB at the recommended
Q8_0 configuration, requiring approximately 148.9 GB at 8K context. Practical context capacity is 64K.CompatibilityComfortable
Calculated fit
Yes
Calculated Uses under 80% of usable memory. Room for a long context and other work.
Recommended quantization
Q8_0
Calculated gguf
Memory required
148.9 GB
Calculated of 217.6 GB usable — 68%
Max practical context
64K
Calculated model supports 64K
Memory budget at 8K context
Model weights ⓘ
141.9 GB Calculated
KV cache ⓘ
1.8 GB Calculated
Runtime overhead ⓘ
5.3 GB Estimated
Total required
148.9 GB Calculated
Headroom ⓘ
68.7 GB Calculated
Highest-precision quantization that leaves headroom: uses 68% of usable memory at 8K context.
Unified memory: weights, KV cache and the OS share the same 256 GB pool. We assume 85% is addressable by the GPU, which matches a headless machine with the wired-memory limit raised.
Mixture of experts: all 140.63B parameters must be resident in memory even though only ~39B are active per token. Memory follows total parameters; speed follows active parameters.
Performance
Estimated performance · recommended Q8_0
Decode, prefill and TTFT below are estimates for Q8_0. We do not have a comparable Q8_0 measurement on this machine.
Estimated decode
—
Estimated Q8_0; calculated range
Estimated prefill
—
Estimated Q8_0; calculated range
Estimated TTFT at 8K
~10.1–21.0 s
Estimated Q8_0; calculated range
Hardware load reference
215 W
Measured machine-level load; not this model run
No throughput figures for this configuration. We do not estimate performance for a model that cannot load.
How the estimate is calculated
- Decode: reading 39.0B active parameters at 8.50 bits/weight takes 39.41 ms at 1200 GB/s x 88% achieved efficiency.
- MoE routing penalty of 15% applied: expert gathers are less bandwidth-efficient than a dense sweep.
- Prefill: 240 TFLOPS (FP16) x 1.69 calibrated against measured prefill on this platform x 22% assumed model-FLOPs utilisation, divided by 2 x 74.1B parameters per token.
- Prefill uses 74.1B effective parameters, not the 39B active in decode: a batch of hundreds of tokens routes across most of the expert pool.
- MoE decode depends on how well the engine batches expert gathers; real results vary more than for dense models.
- Prefill throughput is highly engine-dependent. Flash attention, batch size and quantized KV all move this number substantially, and for sparse mixture-of-experts models it is the least reliable figure we produce.
- This is a calculated estimate, not a measurement. It assumes a single request, a short prompt, no speculative decoding and a warm model already resident in memory.
Estimator version estimator_v1. Stored with every estimated row so old estimates can be regenerated when the model improves.
Submit a benchmarkSubmissions stay pending until reviewed.
This model at other quantizations on this machine
| Quantization | Resident | Disk | Total needed | Utilisation | Fit | Max context |
|---|---|---|---|---|---|---|
MLX 4-bit | 76.6 GB | 76.6 GB | 81.7 GB | 38% | Comfortable | 64K |
Q4_K_M | 81.8 GB | 81.8 GB | 87.0 GB | 40% | Comfortable | 64K |
Q5_K_M | 95.9 GB | 95.9 GB | 101.6 GB | 47% | Comfortable | 64K |
Q8_0recommended | 141.9 GB | 141.9 GB | 148.9 GB | 68% | Comfortable | 64K |
BF16 | 261.9 GB | 261.9 GB | 272.6 GB | 125% | Does not fit | 0 |
Cost of running Mixtral 8x22B on this machineUnited States (federal) · C corporation · 8h/day
Monthly economic cost
$90
Calculated after tax
Codex/Claude Code
$100/mo
≈ $100/mo · local is $10 less
Net cash at purchase
$8,647
Calculated VAT not reclaimable
Total over 5 years
$5,424
Calculated after tax, after resale
Cost per USD/1M tokens
—
Calculated
The $100 comparison uses the Codex Pro 5x / Claude Max 5x plans. A fixed planning conversion is used for USD. This compares monthly spend only: subscriptions have usage limits, local hardware has different capabilities and constraints, and taxes or regional pricing may change the charged amount. Prices checked 7 September 2026.
Purchase-price input: $8,647 in United States (federal), tax/VAT excluded · estimated · Apple Store NL (converted catalogue estimate). This is the localized purchase input; the after-tax economic cost is calculated separately below.
Monthly breakdown
| Depreciation 6,053 over 5 years, straight-line to a 2,594 residual | $100.88 |
| Electricity 9.4 kWh/month at 0.140/kWh | $1.32 |
| Cost of capital 4.0%/yr on 5,621 average capital employed | $18.74 |
| Monthly cost before tax | $120.93 |
| Electricity tax shield Running costs are deductible business expenses | −$0.28 |
| First-year expensing §179 (100.0%) | −$30.26 |
| Monthly economic cost after tax | $90.39 |
Three different numbers, deliberately
Cash cost
$8,647
Money that leaves the bank account on day one, net of reclaimable VAT.
Accounting depreciation
$100.88/month
$6,053 written down over 5 years to a $2,594 residual.
After-tax economic cost
$90.39/month
Depreciation plus running costs plus cost of capital, less the tax those deductions save. This is the figure to compare between machines.
Assumptions and sources (verified 2026-09-07)
VAT rate
0% Official spec
VAT recoverable
0% Official spec
Federal C-corporation estimate at the flat 21% rate. Pass-through entities should use the sole-proprietor estimate as a rougher proxy.
Effective deduction rate
21.00% Calculated
Headline marginal rate 21.00%.
Depreciation
5 years, straight-line Assumption
Residual value
$2,594 (30%) Assumption
Extrapolated from the three-year curve.
Electricity
$0.140/kWh Assumption
Average power draw
53 W Calculated
Load 215 W for 20% of powered hours, idle 13 W for the rest — a machine that is on is not generating tokens the whole time.
Investment allowances
§179 100.0% Official spec
Worth $1,816 in total — first-year expensing that replaces later tax depreciation.
Cost of capital
$18.74/month Assumption
- VAT rate: No US federal VAT · verified 2026-09-07
- Marginal tax rate: IRS Publication 542 — Corporations · verified 2026-09-07
- VAT recoverable fraction: site assumption · verified 2026-09-07
- Useful life: IRS Publication 946 — How To Depreciate Property · verified 2026-09-07
- Electricity price: Site assumption · verified 2026-09-07
Federal planning estimate only, not tax advice. State and local income tax, sales/use tax and incentives are excluded. It assumes 100% business use, a Section 179 election, enough business income to use it, and that the full annual limit remains available.
Mixtral 8x22B on other hardware
| Hardware | Decode | Price | Fit |
|---|
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